SNP

Understand Your
Genetic Risk Profile

Calculate polygenic risk scores for 50+ diseases using validated scores from the PGS Catalog. Upload your DNA data and get comprehensive insights in minutes.

23andMe supportedAncestryDNA supportedVCF supported
50+
Diseases Analyzed
5
Ancestries Supported
PGS
Catalog Validated

How It Works

Get your genetic risk assessment in three simple steps

1

Upload DNA File

Securely upload your genetic data from 23andMe, AncestryDNA, or VCF format.

2

Complete Questionnaire

Add lifestyle and family history data for more accurate risk assessment.

3

Get Results

Receive comprehensive polygenic risk scores for 50+ diseases.

Scientific Rigor Meets
User-Friendly Design

Our calculator uses validated polygenic scores from the PGS Catalog, ensuring accuracy and reliability while presenting results in an easy-to-understand format.

  • PGS Catalog validated polygenic scores
  • Support for 5 major ancestry groups
  • 50+ diseases and traits analyzed
  • Lifestyle and family history integration
  • Comprehensive risk categorization
  • Educational resources included

Example Risk Gauge

Type 2 Diabetes

0255075100
72.5
percentile
Elevated

See How Lifestyle Affects Your Risk

Genetics isn't destiny. Watch how modifiable factors like smoking, exercise, and diet can significantly adjust your genetic risk score.

Example: Reducing Cardiovascular Risk

0%25%50%75%100%0Low RiskHigh Risk
🧬
Genetic Base
60%
🚭
No Smoking
-8%
🏃
Exercise
-12%
🥗
Healthy Diet
-7%
📊
Final Risk
33%

Animation inspired by 3Blue1Brown's educational visualizations

Calculate Your Risk Scores

Upload your DNA data to get started

Complete Pre-Test Questionnaire (Recommended)

Enhance accuracy with lifestyle, family history, and biometric data

Drag & drop or click to upload

Supports 23andMe, AncestryDNA, and VCF formats